| | Player |
POS
| IP | W | L | ERA | WHIP | K | BB |
| 1 |
Spencer Strider
| SP | 123 | 9 | 6 | 3.32 | 1.10 | 163 | 38 |
| 2 |
Bryce Elder
| SP | 58 | 3 | 3 | 4.19 | 1.33 | 48 | 20 |
| 4 |
Grant Holmes
| SP | 119 | 6 | 6 | 4.34 | 1.31 | 118 | 39 |
| 5 |
Spencer Schwellenbach
IL-60
| SP | 166 | 12 | 8 | 3.66 | 1.15 | 161 | 39 |
| 6 |
Chris Sale
IL-60
| SP | 153 | 12 | 7 | 3.30 | 1.11 | 190 | 43 |
| 7 |
AJ Smith-Shawver
IL-60
| SP | 86 | 4 | 5 | 4.41 | 1.30 | 90 | 36 |
| 8 |
Reynaldo Lopez
IL-60
| SP | 158 | 11 | 9 | 4.17 | 1.29 | 166 | 58 |