| | Player |
POS
| IP | W | L | ERA | WHIP | K | BB |
| 1 |
Bowden Francis
| SP | 141 | 7 | 9 | 4.54 | 1.20 | 131 | 41 |
| |
| 2 |
Jose Berrios
| SP | 185 | 10 | 11 | 4.68 | 1.30 | 152 | 55 |
| |
| 3 |
Chris Bassitt
| SP | 172 | 10 | 10 | 4.45 | 1.30 | 153 | 61 |
| 4 |
Max Scherzer
IL-15
| SP | 103 | 6 | 7 | 4.22 | 1.16 | 109 | 31 |
| 5 |
Kevin Gausman
| SP | 180 | 10 | 11 | 4.51 | 1.27 | 174 | 58 |
| 6 |
Alek Manoah
IL-60
| SP | 21 | 1 | 1 | 4.25 | 1.26 | 20 | 9 |